S.Y. B.Sc (Microbiology)

MB – 211: MEDICAL MICROBIOLOGY AND IMMUNOLOGY               [30]

Credit I

MEDICAL MICROBIOLOGY

(15)

1

Definitions:

Incubation period, Viability, Susceptibility, Pathogenicity,

Virulence, Pathogenesis, Lab diagnosis, Epidemic, Sporadic, Endemic, Pandemic

2

2

Study of following pathogens with respect to –Classification, Morphological, Cultural and Biochemical characters,

Antigenic structure, Viability characteristics, Pathogenicity, Pathogenesis, Symptoms, Laboratory diagnosis, Epidemiology, Prophylaxis and Chemotherapy:

Bacteria: a) Escherichia coli b) Staphylococcus aureus

Fungi:       a) Candida               b) Dermatophytes

8

3

Introduction to Chemotherapy

i.    Selective toxicity, Bioavailability MIC, MBC, LD 50

ii.    Antagonism and synergism in drug administration

iii.     Antibiotic sensitivity,

iv.     Antibiotic misuse/antibiotic overuse

v.    Concept of drug resistance (e.g. MRSA, ESBL)

5

Credit II

IMMUNOLOGY

(15)

1

Immunity: Definition, types (Innate and acquired, active and

passive, humoral and cell mediated)

2

2

Formation of blood cells (hematopoiesis)

Myeloid and lymphoid lineages and differentiation process Lymphocytes types

4

3

Antigens and antibodies: definition and concept

1

4

Immunohematology

a.    ABO and Rh blood group systems

b.    Bombay blood group

c.    Biochemistry of blood group substances

d.    Inheritance of ABH antigens

e.    Medico legal applications of blood groups

6

5

Active and Passive Immunization

a.    Active Immunization Whole organism vaccines

i.   Attenuated vaccines

ii.      Inactivated Vaccines

b.    Passive Immunization

Transfer of preformed antibodies

c.    Latest Immunization schedule in India

2